Inhaled steroids and COPD

Inhaled steroids and COPD.

1 Warth A, Herpel E, Schmähl A, et al. Mediastinal angiomyolipomas in a male patient affected by tuberous sclerosis. Eur Respir J 2008; 31: 678–680. 2 Johnson SR, Whale CI, Hubbard RB, Lewis SA, Tattersfield AE. Survival and disease progression in UK patients with lymphangioleiomyomatosis. Thorax 2004; 59; 800–803. 3 Cornog JL Jr, Enterline HT. Lymphangiomyoma, a benign lesion of chyliferous ly...

Inhaled steroids in COPD

T he medical community has made up its mind that, although inhaled corticosteroids reduce exacerbations in patients with chronic obstructive pulmonary disease (COPD), they do not affect disease progression. Despite measurement of forced expiratory volume in one second (FEV1) being widely available and a strong predictor of mortality, the emphasis has moved to softer outcome measures which do sh...

Inhaled steroids for COPD?

Objectives: To determine the effect of long term inhaled corticosteroids on lung function, exacerbations, and health status in patients with moderate to severe chronic obstructive pulmonary disease. Design: Double blind, placebo controlled study. Setting: Eighteen UK hospitals. Participants: 751 men and women aged between 40 and 75 years with mean forced expiratory volume in one second (FEV1) 5...

Inhaled steroids in exacerbations of COPD.

I read with interest the recent article by GUNEN et al. [1], wherein the authors presented the hypothesis that nebulised budesonide might be an alternative to systemic corticosteroids in the treatment of patients with exacerbations of chronic obstructive pulmonary disease (COPD). There are certain points which need discussing regarding their hypothesis of nebulised inhaled corticosteroids in CO...

Inhaled steroids in COPD: reasons for a debate.